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Bethanechol chloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bethanechol chloride图片
CAS NO:590-63-6
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Bethanechol chloride (Carbamyl-β-methylcholine chloride) 是一种拟副交感神经药物,是一种 mAChR 激动剂,通过直接刺激副交感神经系统的 mAChR(M1、M2、M3、M4 和 M5)发挥作用。
Cas No.590-63-6
别名氯贝胆碱; Carbamyl-β-methylcholine chloride
化学名2-carbamoyloxypropyl(trimethyl)azanium;chloride
Canonical SMILESCC(C[N+](C)(C)C)OC(=O)N.[Cl-]
分子式C7H17N2O2.Cl
分子量196.68
溶解度≥ 9.834mg/mL in Water
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.Target: mAChRBethanechol Chloride (Carbamyl-β-methylcholine chloride) is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine, Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is not hydrolyzed by cholinesterase and will therefore have a long duration of action. Oral bethanechol significantly improves contraction pressures and bolus transit in the smooth muscle portion of the esophagus in patients with severe IEM [1]. Bethanechol Chloride (Carbamyl-β-methylcholine chloride) has potential benefit in the treatment of cerebral palsy [2].

References:
[1]. Agrawal, A., et al., Bethanechol improves smooth muscle function in patients with severe ineffective esophageal motility. J Clin Gastroenterol, 2007. 41(4): p. 366-70.
[2]. Carter, W.J., Unexpected benefits of bethanechol in adults with cerebral palsy. Med J Aust, 2008. 189(5): p. 293.