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Clobetasol propionate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Clobetasol propionate图片
CAS NO:25122-46-7
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Clobetasol propionate 是一种有效的选择性 CYP3A5 抑制剂,IC50 为 0.206 μM。
Cas No.25122-46-7
别名丙酸氯倍他索
化学名[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Canonical SMILESCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl
分子式C25H32ClFO5
分子量466.97
溶解度≥ 20.05mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Clobetasol propionate is a anti-inflammatory corticosteroid used to treat various skin disorders.Target: Glucocorticoid ReceptorClobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus (auto immune skin nodules). From Wikipedia.

References:
[1]. http://en.wikipedia.org/wiki/Clobetasol_propionate