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Terazosin HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Terazosin HCl图片
CAS NO:70024-40-7
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议
250mg电议

产品介绍
Terazosin HCl 是一种喹唑啉衍生物,具有竞争性和口服活性 α1-adrenoceptor 拮抗剂。
Cas No.70024-40-7
别名盐酸特拉唑嗪(二水合物)
化学名[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone;dihydrate;hydrochloride
Canonical SMILESCOC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.O.O.Cl
分子式C19H25N5O4.HCl.2H2O
分子量459.92
溶解度≥ 23.0mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR [1].

References:
[1]. Kyncl, J.J., Pharmacology of terazosin: an alpha 1-selective blocker. J Clin Pharmacol, 1993. 33(9): p. 878-83.