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Nalidixic Acid-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nalidixic Acid-d5图片
CAS NO:1189467-36-4
包装与价格:
包装价格(元)
1mg电议
10mg电议

产品名称
萘啶酸 d5
产品介绍
Nalidixic Acid-d5 是 Nalidixic acid 的氘代物。Nalidixic acid,一种喹诺酮类抗生素 (antibiotic),对革兰氏阳性和革兰氏阴性细菌均有效。Nalidixic acid 在较低浓度下以抑菌的方式起作用,而在较高浓度下具有杀菌作用。Nalidixic acid 抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基,并可逆地阻止易感细菌中的 DNA 复制。
生物活性

Nalidixic Acid-d5 is the deuterium labeled Nalidixic acid. Nalidixic acid, aquinoloneantibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit ofDNA gyraseandtopoisomeraseIVand reversibly blocks DNA replication in susceptible bacteria[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

237.27

Formula

C12H7D5N2O3

CAS 号

1189467-36-4

中文名称

萘啶酸 d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.