Cephalexin hydrochloride

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	59695-59-9
包装:	500mg
市场价:	400元

产品名称

盐酸头孢氨苄
Cefalexin hydrochloride
Cephacillin hydrochloride

产品介绍

Cephalexin (Cefalexin) hydrochloride 是一种口服有效的新型半合成头孢菌素抗生素 (antibiotic)，具有广泛的抗菌谱。Cephalexin (Cefalexin) hydrochloride 对多种革兰氏阳性和革兰氏阴性细菌具有抗菌活性。Cephalexin (Cefalexin) hydrochloride 靶向青霉素结合蛋白 (PBPs)，以抑制细菌细胞壁组装。Cephalexin (Cefalexin) hydrochloride 用于肺炎、链球菌性咽喉炎、细菌性心内膜炎等的研究。

生物活性

Cephalexin (Cefalexin) hydrochloride is a potent, orally active new semisynthetic cephalosporinantibioticwith a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride targets penicillin-binding proteins (PBPs) to inhibitbacterialcell wall assembly. Cephalexin (Cefalexin) hydrochloride is used for the research of pneumonia, strep throat, andbacterialendocarditis, et al^[1]^[2].

体外研究
(In Vitro)

Cephalexin (Cefalexin) hydrochloride (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)^[1].
Cephalexin (Cefalexin) hydrochloride inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL forBacillus anthracis,Edwardsiella taFda,Vibrio cholera,Pasteurella multocida,Edwardsiella tarda,Alcaligenes spandProteus rettgeri, respectively^[2].

体内研究
(In Vivo)

Cephalexin (Cefalexin) hydrochloride (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial^[2].

Animal Model:	Male Swiss-Webster mice with infected bacterial^[2]
Dosage:	0-50 mg/kg
Administration:	Oral administration; for 3.5 hours
Result:	Had antibacterial activity againstStreptococcus pyogenes,Streptococcus pneumoniae,Staphylococcus aureusand severalgram-negative speciesmice.

Clinical Trial

分子量

383.85

Formula

C₁₆H₁₈ClN₃O₄S

CAS 号

59695-59-9

中文名称

盐酸头孢氨苄

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.