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Dihydrochelerythrine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dihydrochelerythrine图片
CAS NO:6880-91-7
包装与价格:
包装价格(元)
10 mM * 1 mL in DMSO电议
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
二氢白屈菜红碱
12,13-Dihydrochelerythrine
产品介绍
二氢白屈菜红碱(Dihydrochelerythrine)是从延胡索分离出的天然化合物,具抗真菌等活性。
生物活性

Dihydrochelerythrine is a natural compound isolated fromCorydalis yanhusuo; has antifungal activity. IC50 value: Target: in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner [1]. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction ofapoptosisand necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry [2]. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively [3].

分子量

349.38

性状

Solid

Formula

C21H19NO4

CAS 号

6880-91-7

中文名称

二氢白屈菜红碱

结构分类
  • Alkaloids
  • Quinoline Alkaloids
来源
  • Plants
  • Papaveraceae
  • Macleaya cordata(Willd.) R. Br.
  • Plants
  • Papaveraceae
  • Corydalis yanhusuoW. T. Wang
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month
溶解性数据
In Vitro: 

DMSO : 20.83 mg/mL(59.62 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM2.8622 mL14.3111 mL28.6221 mL
5 mM0.5724 mL2.8622 mL5.7244 mL
10 mM0.2862 mL1.4311 mL2.8622 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。