CAS NO: | 2584947-54-4 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PXS-6302 is an irreversiblelysyl oxidaseinhibitor withIC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1]. | ||||||||
IC50& Target | 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4)[1] | ||||||||
体外研究 (In Vitro) | PXS-6302 demonstrates high permeability to across a monolayer of cells, such as Caco-2 or MDCKII cells[1]. | ||||||||
体内研究 (In Vivo) | PXS-6302 inhibits LOX, reduces crosslinking and improves scar appearance in porcine models of excisional and burn injury[1].
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分子量 | 265.25 | ||||||||
Formula | C10H10F3NO2S | ||||||||
CAS 号 | 2584947-54-4 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |