CAS NO: | 125035-83-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | 7-Oxostaurosporine is a potent protein kinase C (PKC) inhibitor that effectively inhibits tumor growth by inducingapoptosisand inhibiting the nuclear factor (NF)-κB/p-p65 pathway[1][2]. |
体外研究 (In Vitro) | 7-Oxostaurosporine (50 nM, 24 h)可以导致 CHO 细胞中质膜鞘磷脂增加,但不会改变神经酰胺含量[1]。 |
体内研究 (In Vivo) | 7-Oxostaurosporin(6 mg/kg,每天一次,静脉注射)显着降低肿瘤生长,肿瘤生长抑制(TGI)为 56.1%,对体重无明显影响[2]。 |
分子量 | 480.51 |
Formula | C28H24N4O4 |
CAS 号 | 125035-83-8 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |