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Dexamethasone-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dexamethasone-d4图片
CAS NO:2305607-27-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
Hexadecadrol-d4
Prednisolone F-d4
产品介绍
Dexamethasone-d4 是 Dexamethasone 氘代物。Dexamethasone (Hexadecadrol) 是一种糖皮质激素受体 (glucocorticoid receptor) 激动剂。Dexamethasone 还显着降低中性粒细胞的 CD11b,CD18 和 CD62L 表达,以及单核细胞的 CD11b 和 CD18 表达。Dexamethasone 有潜力用于 COVID-19 的研究。Dexamethasone 在 LPS 诱导的巨噬细胞炎症反应中,抑制含有炎性 miRNA-155 的外泌体的产生。
生物活性

Dexamethasone-d4 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is aglucocorticoid receptoragonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

396.49

Formula

C22H25D4FO5

CAS 号

2305607-27-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.