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5-Methoxyflavone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-Methoxyflavone图片
CAS NO:42079-78-7
规格:≥98%
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议
1g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW) 252.26
Formula C16H12O3
CAS No. 42079-78-7
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO:
Water:
Ethanol:
Solubility (In vivo)
Synonyms
SMILES Code
实验参考方法
In Vitro

In vitro activity: treatment with 5-methoxyflavone at various times (3, 6, 12, 18 and 24 h) in MOLT-4 cells results in a time dependent reduction in the levels of antiapoptotic proteins cFLIP, Mcl-1 and an increase in the proapoptotic protein BAX. 5-MF induces both TRAIL-R1(DR4) and TRAIL-R2 (DR5) in a time-dependent manner.


Kinase Assay:


Cell Assay: OLT-4 or U937 or PBMC cells are treated with DMF or TMF or PMF, 5-methoxyflavone or 2'-methoxyflavone at various concentrations for 24 h, then the cell viability is determined by the MTT assay.

In Vivo
Animal model
Formulation & Dosage
References J Nat Prod. 2015 Nov 25;78(11):2704-11.