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L-Asparagine-N-Fmoc,N-beta-trityl-15N2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Asparagine-N-Fmoc,N-beta-trityl-15N2图片
CAS NO:204633-98-7
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
L-Asparagine-N-Fmoc,N-beta-trityl-15N2 是一种 15N 标记的 Deruxtecan。Deruxtecan 是毒性药物和 linker 的偶联物。毒性药物是 DX-8951 (DXd) 衍生物,linker 是马来酰亚胺-GGFG 肽。Deruxtecan 可用于合成 DS-8201 和 U3-1402。
生物活性

L-Asparagine-N-Fmoc,N-beta-trityl-15N2 is a 15N-labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

分子量

598.66

Formula

C38H3215N2O5

CAS 号

204633-98-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.