您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 6-Dehydrogingerdione
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
6-Dehydrogingerdione
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
6-Dehydrogingerdione图片
CAS NO:76060-35-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
6-Dehydrogingerdione 通过活性氧介导 DR5 的增加,使人肝母细胞瘤 Heg2 细胞对 TRAIL 诱导的凋亡敏感。
生物活性

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to TRAIL-inducedapoptosisvia reactive oxygen species-mediated increase of DR5[1].

体外研究
(In Vitro)

6-Dehydrogingerdione could trigger apoptotic cell death via both mitochondrial- and Fas receptor-mediated pathways[1].
6-Dehydrogingerdione (6-DG) up-regulates Ser-15 phosphorylation and evoked p53 nuclear translocation[1].
6-Dehydrogingerdione (6-DG) induces mitochondrial apoptotic pathway[1].

Apoptosis Analysis[1]

Cell Line:Hep G2 cells.
Concentration:0, 50, 100 μM.
Incubation Time:24 h.
Result:Induced Apoptosis in Hep G2 Cells.
分子量

290.35

Formula

C17H22O4

CAS 号

76060-35-0

结构分类
  • Phenols
  • Monophenols
来源
  • Plants
  • Zingiberaceae
  • Zingiber officinale
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.