DS17701585 (Compound 11) 是一种选择性的、具有口服活性的EP300和CBP抑制剂,对 CBP、EP300、H3K27和SOX2的IC50值分别为 0.040、0.15、0.45 和 0.70 μM。DS17701585 可用于癌症的研究。
生物活性 | DS17701585 (Compound 11) is a highly selective, orally activeEP300andCBPinhibitor withIC50values of 0.040, 0.15, 0.45 and 0.70 μM against CBP, EP300,H3K27andSOX2. DS17701585 can be used forcancerresearch[1]. |
IC50& Target | H3K27 0.45 μM (IC50) | SOX2 0.70 μM (IC50) | EP300 0.04 μM (IC50) | CBP 0.15 μM (IC50) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |