AChE-IN-5 (compound 5) 对AChE/5-HT1A/SERT表现出很强的体外生物活性,并表现出良好的可透过血脑屏障。AChE-IN-5 对 AChE 的 IC50值为 2.29 nM,对 5-HT1A的 EC5058.6 nM 和对 SERT 的 IC50值为 2.29 nM。具有口服活性。
生物活性 | AChE-IN-5 (compound 5) exhibits strong in vitro bioactivity againstAChE/5-HT1A/SERTand exhibits good BBB permeability. AChE-IN-5 shows IC50value 2.29 nM againstAChE, EC5058.6 nM against 5-HT1Aand IC50 value against SERT. Orally active[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |