CXCR2 antagonist3 (compound 11h) is a potent antagonist ofCXC chemokine receptor2 (CXCR2).CXCR2 antagonist3 demonstrates double-digit nanomolar potencies againstCXCR2and significantly inhibited neutrophil infiltration into the air pouch.CXCR2 antagonist3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3⁺T lymphocytes into the Pan02 tumor tissues^[1].

362.38

C₁₇H₁₅FN₂O₄S

2647464-92-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.