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Fenofibric acid-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fenofibric acid-d6图片
CAS NO:1092484-69-9
包装与价格:
包装价格(元)
1mg电议
10mg电议

产品名称
非诺贝特酸 d6
产品介绍
Fenofibric acid-d6 是 Fenofibric acid 的氘代物。Fenofibric acid 是 fenofibrate 的活性代谢物,为PPAR激动剂,对 PPARα,PPARγ 和 PPARδ 的EC50值分别为 22.4 μM,1.47 μM 和 1.06 μM;Fenofibric acid 同时可抑制COX-2的活性,IC50值为 48 nM。
生物活性

Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is aPPARactivitor, withEC50s of 22.4 μM, 1.47 μM, and 1.06 μM forPPARα,PPARγandPPARδ, respectively; Fenofibric acid also inhibitsCOX-2enzyme activity, with anIC50of 48 nM.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

324.79

Formula

C17H9D6ClO4

CAS 号

1092484-69-9

中文名称

非诺贝特酸 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.