Valdecoxib-d3 (SC 65872-d3) is the deuterium labeled Valdecoxib. Valdecoxib is a highly potent and selective inhibitor ofCOX-2, withIC₅₀s of 5 nM and 140 μM forCOX-2andCOX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

317.38

C₁₆H₁₁D₃N₂O₃S

1219794-90-7

伐地考昔 D3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.