Firocoxib-d4 (ML 1785713-d4) is the deuterium labeled Firocoxib. Firocoxib (ML 1785713) is a potent, selective and orally activeCOX-2inhibitor with anIC₅₀of 0.13 μM. Firocoxib shows 58-fold more selective forCOX-2thanCOX-1(IC₅₀of 7.5 μM). Firocoxib has anti-inflammatory effects^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

340.43

C₁₇H₁₆D₄O₅S

1325700-11-5

非罗考昔 d4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.