Lyn peptide inhibitor TFA

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

Lyn peptide inhibitor TFA 是一种有效的，可以细胞渗透的抑制剂，抑制Lyn偶联的IL-5受体相关信号通路，同时保持其他信号的完整。Lyn peptide inhibitor TFA 可以阻断 Lyn 的激活，抑制 Lyn 酪氨酸激酶与 IL-3/GM-CSF/IL-5 受体的 βc 亚基结合。Lyn peptide inhibitor TFA可用于哮喘、过敏等嗜酸性疾病的研究。

生物活性

Lyn peptide inhibitor TFA is a potent and cell-permeable inhibitor ofLyn-coupledIL-5 receptorsignaling pathway, while keeping other signals intact. Lyn peptide inhibitor TFA blocks Lyn activation and inhibits the binding ofLyn tyrosine kinaseto βc subunit of IL-3/GM-CSF/IL-5 receptors. Lyn peptide inhibitor TFA can be used for study of asthma, allergic, and other eosinophilic disorders^[1].

IC₅₀& Target^[1]^[2]

IL-5

IL-3

分子量

2484.90

Formula

C₁₁₆H₁₈₆F₃N₃₀O₂₆

Sequence

Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2

Sequence Shortening

Stearoyl-YGYRLRRKWEEKIPNP-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.