Nalfurafine is a highly potent, selective and orally bioavailable antipruritic/anti-itch drug marketed in Japan for the treatment of uremic pruritus in individuals with chronic kidney disease undergoing hemodialysis. It acts as a potent, selective, centrally-penetrant κ-opioid receptor (KOR) agonist, and is the first and currently the only selective KOR agonist to have been approved for clinical use. It has also been referred to as the 'first non-narcotic opioid drug' in history.
纯度:≥98%
CAS:152657-84-6