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Azido-PEG4-Val-Cit-PAB-MMAE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Azido-PEG4-Val-Cit-PAB-MMAE图片
CAS NO:1869126-64-6
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Azido-PEG4-Val-Cit-PAB-MMAE 是抗体偶联药物的一部分 (drug-linker conjugate for ADC)。由多肽 linker 和抗有丝分裂剂 MMAE (一种 tubulin 抑制剂) 连接而成。
Cas No.1869126-64-6
分子式C69H113N13O17
分子量1396.71
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH[1].

[1]. Moreadith R, et, al. Polyoxazoline antibody drug conjugates. WO2016019340A1.