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MC-Val-Cit-PAB-DX8951
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MC-Val-Cit-PAB-DX8951图片
CAS NO:2504068-28-2
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
MC-Val-Cit-PAB-DX8951 (MC-Val-Cit-PAB-DX8951) 是一种用于 ADC 的药物-接头偶联物。 MC-Val-Cit-PAB-DX8951 由 DNA 拓扑异构酶 I DX-8951 和组织蛋白酶可切割的 ADC 接头组成。
Cas No.2504068-28-2
别名MC-Val-Cit-PAB-DX8951
分子式C53H60FN9O12
分子量1034.1
储存条件4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MC-Val-Cit-PAB-DX8951 is a drug-linker conjugate for ADC. MC-Val-Cit-PAB-DX8951 is composed of a DNA topoisomerase I DX-8951 and a cathepsin cleavable ADC linker.

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Anish Thomas, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262.