CAS NO: | 98791-67-4 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | (R)-(+)-Bay-K-8644 is acalcium channelinhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+currents (IBa) (IC50=975 nM). | ||||||||||||||||
IC50& Target | IC50: 975 nM (IBa)[1] | ||||||||||||||||
体外研究 (In Vitro) | (R)-(+)-Bay-K-8644, a conventional racemic mixture of Bay K 8644, is widely used as an L-type Ca2+channel agonist. Each optical isomer possesses opposite effects on IBa, (R)-(+)-Bay-K-8644 as an antagonist and S(-)-Bay K 8644 as an agonist. (R)-(+)-Bay-K-8644 inhibits Ba2+currents (IBa) (IC50=975 nM). When (R)-(+)-Bay-K-8644 (0.5 μM) is applied, IBais suppressed to 71±10% of control. In the presence of (R)-(+)-Bay-K-8644IBa[1]. (R)-(+)-Bay-K-8644 is a calcium channel inhibitor[2]. | ||||||||||||||||
分子量 | 356.30 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C16H15F3N2O4 | ||||||||||||||||
CAS 号 | 98791-67-4 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 300 mg/mL(841.99 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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