您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > (R)-Phenylpiracetam
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
(R)-Phenylpiracetam
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(R)-Phenylpiracetam图片
CAS NO:949925-07-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
MRZ 9547
产品介绍
(R)-Phenylpiracetam (MRZ 9547) 是多巴胺转运体 (DAT) 抑制剂,Ki值和IC50值分别为 14.8 μM、65.5 μM。(R)-Phenylpiracetam 可用于神经或神经精神疾病的研究。
生物活性

(R)-Phenylpiracetam (MRZ 9547) is adopamine transporter(DAT) inhibitor (Ki: 14.8 μM;IC50: 65.5 μM). (R)-Phenylpiracetam can be used for the research of the neurological or neuropsychiatric disorders[1][2].

IC50& Target

Ki: 14.8 μM (DAT); IC50: 65.5 μM (DAT)[2]

体外研究
(In Vitro)

(R)-Phenylpiracetam displaces the binding of [125I] RTI-55 (IC50= 4.82 μM) to human recombinant DAT expressed in CHO-K1 cells[2].

体内研究
(In Vivo)

(R)-Phenylpiracetam (50 mg/kg; p.o. or i.p.; single-dose) reaches the mouse brain tissue 15 min after administration[1].
(R)-Phenylpiracetam (10, 25, 50 mg/kg; p.o.; pretreatment for 7 days) dose-dependently reduces paw oedema and the antinociceptive response on carrageenan induced mouse[1].

分子量

218.25

Formula

C12H14N2O2

CAS 号

949925-07-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.