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AZ-1355
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AZ-1355图片
CAS NO:75451-07-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
AZ-1355 是一种有效的降脂药,并能够抑制体内血小板凝集,提高体外前列腺素 I2/血栓素A2的比例。
生物活性

AZ-1355 is an effctive lipid-lowering compound, which also inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2ratio in vitro.

IC50& Target[1]

Prostaglandin I2

 

Thromboxane A2

 

体内研究
(In Vivo)

AZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rat. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats. AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice[1].

分子量

299.32

Formula

C17H17NO4

CAS 号

75451-07-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.