CAS NO: | 694466-00-7 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | hCAI/II-IN-6 is an orally activehumancarbonic anhydrase(CA) inhibitor. hCAI/II-IN-6 selectively inhibits hCA II and hCA VII isoforms withKivalues of 220, 4.9, 6.5 and >50000 nM for hCA I, hCA II , hCA VII and hCA XII respectively. hCAI/II-IN-6 shows anticonvulsant activity and anti maximal electroshock (MES) activity in vivo. hCAI/II-IN-6 can be used for the research of epilepsy[1]. | ||||||||||||||||
体外研究 (In Vitro) | hCAI/II-IN-6 (0-50 μM) inhibits hCA I, hCA II , hCA VII and hCA XII activities withKivalues of 220, 4.9, 6.5 and >50000 nM, respectively[1]. | ||||||||||||||||
体内研究 (In Vivo) | hCAI/II-IN-6 (30-100mg/kg; i.p. once) shows good anticonvulsant effect in vivo[1].hCAI/II-IN-6 (30 mg/kg; p.o. once) shows anti-MES activity in vivo[1].
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分子量 | 388.48 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H24N4O3S | ||||||||||||||||
CAS 号 | 694466-00-7 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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