BACE1-IN-2 是一种选择性的BACE1抑制剂,IC50为 22 nM。
生物活性 | BACE1-IN-2 is a 1,4-Oxazine β-Secretase 1 (BACE1) inhibitor with anIC50of 22 nM[1]. |
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体外研究 (In Vitro) | BACE1-IN-2 (Compound 3) is 10-fold more potent toward BACE1 than BACE2, inhibition of which may lead to hair depigmentation. BACE1-IN-2 inhibits hAβ42 cell with an IC50of 6.0 nM[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |