CAS NO: | 74195-83-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Anagyrine ((-)-Anagyrine) hydrochloride is a quinolizidine alkaloid that has been found inLupinus albus. Anagyrine hydrochloride binds tomuscarinic and nicotinic acetylcholine receptorswithIC50values of 132 and 2096 μM respectively. Anagyrine hydrochloride is a potent and effective desensitizer ofnAChR, and Anagyrine hydrochloride can directly, without metabolism, desensitizenAChR[1][2][3]. |
体外研究 (In Vitro) | Anagyrine 在 SH-SY5Y 和 TE-671 两种细胞系中均充当部分激动剂,EC50值分别为 4.2 和 231 μM。 Anagyrine 是 nAChR 的脱敏剂,在 SH-SY5Y 和 TE-671 细胞中的DC50值分别为 6.9 和 139 μM[3]。 |
分子量 | 280.79 |
Formula | C15H21ClN2O |
CAS 号 | 74195-83-8 |
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |