CAS NO: | 94424-50-7 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamineD2 receptoragonist. Quinagolide hydrochloride is an inhibitor ofprolactin. Quinagolide hydrochloride down-regulatesAKTlevels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research ofcancer[1][2]. | ||||||||||||||||
体外研究 (In Vitro) | Quinagolide hydrochloride (100 nM; 48 h) reduces non-ergot dopamine receptor 2 (DRD2) mRNA expression in ectopic lines[2].Quinagolide hydrochloride (100 nM; 48 h) inhibits the invasive properties of endometrial mesenchymal stromal cells (E-MSCs)[2].Quinagolide hydrochloride (100 nM; 24 h) significantly reduces the endothelial differentiation of E-MSCs[2]. Western Blot Analysis[2]
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体内研究 (In Vivo) | Quinagolide hydrochloride (0.03-0.6 mg/kg; s.c. once daily for 2 month) effectively inhibits tumor growth in vivo[1].
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Clinical Trial | |||||||||||||||||
分子量 | 432.02 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C20H34ClN3O3S | ||||||||||||||||
CAS 号 | 94424-50-7 | ||||||||||||||||
中文名称 | 盐酸喹高利特 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 3.85 mg/mL(8.91 mM;Need ultrasonic) 配制储备液
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