包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Allo-aca TFA, aleptinpeptidomimetic, is a potent, specificleptinreceptorantagonist peptide. Allo-aca TFA blocksleptinsignaling and action in numerous in vitro and in vivo models[1][2]. |
体外研究 (In Vitro) | Allo-aca TFA inhibits leptin-induced proliferation of MDA-MB-231 cells at 50 pM concentration. Allo-aca TFA inhibits leptin-induced proliferation of MCF-7 cells with an IC50of 200 pM[1]. |
体内研究 (In Vivo) | In an MDA-MB-231 orthotopic mouse xenograft model, Allo-aca TFA administered subcutaneously significantly extends the average survival time from 15.4 days (untreated controls) to 24 and 28.1 days at 0.1 and 1mg/kg/day doses, respectively[1]. |
分子量 | 1188.21 |
Formula | C50H76F3N13O17 |
Sequence Shortening | {H-allo}-TE-{Nva}-VALSR-{Aca}-NH2 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |