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Enmein
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Enmein图片
CAS NO:3776-39-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
Enmein 从I. serra中分离,具有免疫抑制作用。
生物活性

Enmein is isolated fromI. serrawith immunosuppressive effect[1].

体外研究
(In Vitro)

Enmein shows significant inhibitory effect toward K562 with an IC50value ranging from 3.2 μg/ml to 8.2 μg/ml[2].
Enmein (3.13-25 μg/ml; 48 hours) has inhibitory effect on lymphocytes with significant difference within concentration from 6.25 μg/ml to 25 μg/ml[1].
Enmein (5.5-22 μg/ml; 48 hours) causes the percentage of S stage cells decreased from 19% to 6%, causes the percentage of G2/M stage cells to decrease from 2% to 0.4%[1].

Cell Viability Assay[1]

Cell Line:Splenic lymphocyte cells
Concentration:3.13, 6.25, 12.5, 25 μg/ml
Incubation Time:48 hours
Result:Exhibited an IC50value of 17 μg/ml in splenic lymphocytes.

Cell Cycle Analysis[1]

Cell Line:Splenic lymphocyte cells
Concentration:5.5 μg/ml, 11 μg/ml, 22 μg/ml
Incubation Time:48 hours
Result:Caused S stage cells and G2/M stage cells decreased.
体内研究
(In Vivo)

Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression[1].

Animal Model:Balb/c mice[1]
Dosage:6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg
Administration:Injected to ear; 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg; 5 days
Result:Had inhibitory effect on IL-2 release in blood.
分子量

362.42

Formula

C20H26O6

CAS 号

3776-39-4

结构分类
  • Others
来源
  • Plants
  • Labiatae
  • Rabdosia serra(Maxim.) Hara
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.