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Cajanin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cajanin图片
CAS NO:32884-36-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Cajanin 是一种有效且具有口服活性的抗黑色素剂。Cajanin 在 MNT1 细胞中显示出抗增殖活性。Cajanin 有效降低黑色素含量。Cajanin 下调 MITF、酪氨酸酶、TRP-1 和 Dct (TRP-2) 的 mRNA 和蛋白质表达水平。Cajanin 诱导细胞周期停滞在 G2/M 和 S 期。Cajanin 刺激成骨细胞增殖。Cajanin 具有研究人类色素沉着过度症和更年期骨质疏松症的潜力。
生物活性

Cajanin is a potent and orally activeanti-melanogenicagent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF,tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis[1][2].

体外研究
(In Vitro)

Cajanin shows strong mitogenic as well as differentiation-promoting effects on osteoblasts[2].
Cajanin induces the phosphorylation of both Erk1/2 and Akt[2].

体内研究
(In Vivo)

Cajanin (10 mg/kg, p.o.; daily for 30 consecutive days) increases the BMD levels in all anatomical regions of the skeleton studied in Sprague Dawley rats[1].

分子量

300.26

Formula

C16H12O6

CAS 号

32884-36-9

结构分类
  • Flavonoids
  • Isoflavones
  • Phenols
  • Polyphenols
来源
  • Plants
  • other families
  • red seaweeds
  • Plants
  • Leguminosae
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.