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5-hydroxypyrazine-2-carboxylic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-hydroxypyrazine-2-carboxylic acid图片
CAS NO:34604-60-9
包装:100mg
市场价:1061元

产品介绍
5-Hydroxypyrazine-2-Carboxylic Acid,抗结核药物吡嗪酰胺 (PZA) 的代谢物。
Cas No.34604-60-9
别名5-羟基吡嗪-2-羧酸
化学名5-hydroxypyrazine-2-carboxylic acid
Canonical SMILESOC1=NC=C(C(O)=O)N=C1
分子式C5H4N2O3
分子量140.1
溶解度≥ 7 mg/mL in DMSO, ≥ 7.63 mg/mL in Water
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5-Hydroxypyrazine-2-Carboxylic Acid, a metabolite of anti-tuberculosis drug pyrazinamide (PZA).

References:
[1]. Huq, Fazlul; Hossain, Zahed. Molecular modelling analysis of the metabolism of pyrazinamide. Journal of Pharmacology and Toxicology (2006), 1(6), 505-515.
[2]. Mehmedagic, Aida; Verite, Philippe; Menager, Sabine et al. Investigation of the effects of concomitant caffeine administration on the metabolic disposition of pyrazinamide in rats. Biopharmaceutics & Drug Disposition (2002), 23(5), 191-195.