CAS NO: | 3093-66-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Fluphenazine dimaleate is a potent, orally active phenothiazine-baseddopamine receptorantagonist. Fluphenazine dimaleate blocks neuronal voltage-gatedsodium channels. Fluphenazine dimaleate acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dimaleate can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dimaleate can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibitSARS-CoV-2[1][2][3][4][6]. | ||||||||||||||||
IC50& Target | Dopamine receptor, Sodium channels, SARS-CoV-2[1][2] | ||||||||||||||||
体内研究 (In Vivo) | Fluphenazine (1 mg/kg; IG, treated from day 6 to day 15 of gestation) causes malformations in pregnant mice[5].
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Clinical Trial | |||||||||||||||||
分子量 | 669.67 | ||||||||||||||||
Formula | C30H34F3N3O9S | ||||||||||||||||
CAS 号 | 3093-66-1 | ||||||||||||||||
中文名称 | 氟奋乃静马来酸氢盐 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |