| CAS NO: | 91374-21-9 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | Ropinirole (SKF 101468) is an orally active, potent D3/D2receptor agonist with aKiof 29 nM forD2receptor. Ropinirole haspEC50s of 7.4, 8.4 and 6.8 for hD2, hD3and hD4receptors, respectively. Ropinirole has no affinity for the D1receptors. Ropinirole has the potential for Parkinson's disease[1][2]. | ||||
| IC50& Target[1][2] |
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| 体外研究 (In Vitro) | Ropinirole has affinity for D3receptors of 10-20 fold higher than the D2and D4receptors. Ropinirole is weakly active at alpha 2-adrenoceptors and 5-HT2receptors but inactive at 5-HT1, benzodiazepine and gamma-aminobutyric acid receptors or alpha 1 and beta-adrenoceptors[1][2]. | ||||
| 体内研究 (In Vivo) | Ropinirole (0.1-10 mg/kg; i.p.) decreases intracranial self-stimulation (ICSS) thresholds and induces anxiolytic- and antidepressive-like effects without affecting motor activity or spatial memory[2]. | ||||
| Clinical Trial | |||||
| 分子量 | 260.37 | ||||
| Formula | C16H24N2O | ||||
| CAS 号 | 91374-21-9 | ||||
| 中文名称 | 罗匹尼罗 | ||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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