CAS NO: | 123039-93-0 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Dihydrexidine (DAR-0100) is a high potent, selective and full efficacyD1-likedopamine receptor(D1/D5)agonist with anIC50of 10 nM for D1 receptor. Dihydrexidine exhibits potent antiparkinsonian activity[1][2][3][4]. Dihydrexidine can stimulateYAPphosphorylation[5]. | ||||||||
IC50& Target | IC50: 10 nM (D1 dopamine receptor), D5 dopamine receptor, 660 nM (D1 dopamine receptor)[1] | ||||||||
体外研究 (In Vitro) | Dihydrexidine (DAR-0100) strongly increased YAP phosphorylation in U2OS cells[5]. | ||||||||
体内研究 (In Vivo) | Dihydrexidine has poor oral bioavailability and a relatively short half-life of 1 to 2 h[3].
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Clinical Trial | |||||||||
分子量 | 267.32 | ||||||||
Formula | C17H17NO2 | ||||||||
CAS 号 | 123039-93-0 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |