(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist ofNeurokinin B(Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A^[1].

在大鼠中，(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) 显着减少 Substance P- 和 Neurokinin B-， 但不减少乙酰胆碱或 Neurokinin A 诱导的流涎。(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 可将麻醉大鼠的血压降低 35% 至 40%^[2]。

1326.50

C₆₇H₈₇N₁₅O₁₄

109212-72-8

D-{D-Pro}-HDF-{D-Trp}-V-{D-Trp}-L-{Nle}-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.