CAS NO: | 60117-17-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | [Met5]-Enkephalin, amide is an agonist forδ opioid receptorsas well as putativeζ (zeta) opioid receptors. |
IC50& Target | δ and ζ opioid receptor[1] |
体外研究 (In Vitro) | [Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture[1]. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine[2]. |
分子量 | 572.68 |
Formula | C27H36N6O6S |
CAS 号 | 60117-17-1 |
Sequence | Tyr-Gly-Gly-Phe-Met-NH2 |
Sequence Shortening | YGGFM-NH2 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |