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[Met5]-Enkephalin,amide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
[Met5]-Enkephalin,amide图片
CAS NO:60117-17-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
5-Methionine-enkephalin amide
产品介绍
[Met5]-Enkephalin, amide 是一种δζ阿片受体 (opioid receptor) 激动剂。
生物活性

[Met5]-Enkephalin, amide is an agonist forδ opioid receptorsas well as putativeζ (zeta) opioid receptors.

IC50& Target

δ and ζ opioid receptor[1]

体外研究
(In Vitro)

[Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture[1]. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine[2].

分子量

572.68

Formula

C27H36N6O6S

CAS 号

60117-17-1

Sequence

Tyr-Gly-Gly-Phe-Met-NH2

Sequence Shortening

YGGFM-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.