Conopressin S 是从Conus striatus中分离出来的一种多肽，能与血管加压素V1b 受体 (AVPR1B)高亲和力结合，Ki值为8.3 nM。
| 生物活性 | Conopressin S, isolated fromConus striatus, shows high affinity withvasopressin V1b receptor (AVPR1B), with aKiof 8.3 nM[1]. |
| IC50& Target | |
| Clinical Trial | |
| 分子量 | |
| Formula | |
| CAS 号 | |
| Sequence | Cys-Ile-Ile-Arg-Asn-Cys-Pro-Arg-Gly-NH2(Disulfide bridge: Cys1-Cys6) |
| Sequence Shortening | CIIRNCPRG-NH2 (Disulfide bridge: Cys1-Cys6) |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Solvent & Solubility | In Vitro: H2O Peptide Solubility and Storage Guidelines: 1. Calculate the length of the peptide. 2. Calculate the overall charge of the entire peptide according to the following table: | | Contents | Assign value | | Acidic amino acid | Asp (D), Glu (E), and the C-terminal -COOH. | -1 | | Basic amino acid | Arg (R), Lys (K), His (H), and the N-terminal -NH2 | +1 | | Neutral amino acid | Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) | 0 |
3. Recommended solution: | Overall charge of peptide | Details | | Negative (<0) | 1. Try to dissolve the peptide in water first.
2. If water fails, add NH4OH (<50 μL).
3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide. | | Positive (>0) | 1. Try to dissolve the peptide in water first.
2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO. | | Zero (=0) | 1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration. |
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