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Sitagliptin-d4 phosphate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sitagliptin-d4 phosphate图片
CAS NO:1432063-88-1
包装:1mg
市场价:11500元

产品名称
磷酸西他列汀 d4 (磷酸盐)
产品介绍
Sitagliptin-d4 (MK-0431-d4) phosphate 是 Sitagliptin phosphate 的氘代物。Sitagliptin phosphate (MK-0431 phosphate) 是一种有效的DPP4抑制剂,在 Caco-2 细胞中,IC50值为 19 nM。
生物活性

Sitagliptin-d4 (MK-0431-d4) phosphate is the deuterium labeled Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor ofDPP4with anIC50of 19 nM in Caco-2 cell extracts[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

509.33

Formula

C16H14D4F6N5O5P

CAS 号

1432063-88-1

中文名称

磷酸西他列汀 d4 (磷酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.