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Amphotericin B methyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Amphotericin B methyl ester图片
CAS NO:36148-89-7
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
Amphotericin B methyl ester 是多烯类抗生素 Amphotericin B (A634250) 的甲酯衍生物。Amphotericin B methyl ester 是胆固醇结合物,具有显著的抗真菌活性。Amphotericin B methyl ester 干扰 HIV-1 颗粒的产生,抑制 HIV-1 的复制。
生物活性

Amphotericin B methyl ester is the methyl ester derivative of the polyeneantibioticAmphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disruptsHIV-1particle production and potently inhibitsHIV-1replication[1][2].

体外研究
(In Vitro)

Amphotericin B methyl ester inhibits HIV-1 particle production with no significant effect on Gag binding to the plasma membrane, Gag association with lipid rafts, or Gag multimerization[1].

分子量

938.11

Formula

C48H75NO17

CAS 号

36148-89-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
In Vitro: 

DMSO : 50 mg/mL(53.30 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM1.0660 mL5.3299 mL10.6597 mL
5 mM0.2132 mL1.0660 mL2.1319 mL
10 mM0.1066 mL0.5330 mL1.0660 mL