Toddaculin is a natural coumarin that can induce differentiation andapoptosisin leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity^[1][2][3].

Toddaculin (5-250 μM; 24-72 h) shows anti-proliferative activity in U-937 cells, with an IC₅₀of 51.38 μM^[1].
Toddaculin (25-250 μM; 24-48 h) induces partial differentiation in U-937 leukemic cells^[1].

274.31

Solid

C₁₆H₁₈O₄

4335-12-0

飞龙掌血素

• Phenylpropanoids
• Coumarins

• Plants
• Rutaceae
• Toddalia asiatica(L.) Lam.

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

DMSO : 50 mg/mL(182.28 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。