Raclopride-d5 (hydrochloride) is the deuterium labeled Raclopride. Raclopride is adopamine D₂/D₃receptorantagonist, which binds toD₂andD₃receptors with dissociation constants (K_is) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D₁and D₄receptors with K_is of 18000 nM and 2400 nM, respectively^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

352.27

C₁₅H₁₆D₅Cl₃N₂O₃

1217623-85-2

雷氯必利 d5 (盐酸盐)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.