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Mevalonic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mevalonic acid图片
CAS NO:150-97-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
MVA
产品介绍
Mevalonic acid (MVA) 是甲羟戊酸途径 (mevalonate pathway) 的前体物质,对细胞生长和增殖至关重要。Mevalonic acid 在体外能有效抑制 Simvastatin (HY-17502) 诱导的 C2C12 细胞活力下降,可用于肌病和心力衰竭的研究。
生物活性

Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibitingSimvastatin(HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure[1][2].

体外研究
(In Vitro)

Mevalonic acid (80, 90, 100, 110 μM; 72 h) shows prevention of simvastatin-induced loss of viability of C2C12myotube cells in vitro[1].

Cell Viability Assay[1]

Cell Line:C2C12 cells (simvastatin-induced)
Concentration:80, 90, 100, 110 μM
Incubation Time:72 h
Result:Showed no decline in cell viability.
Clinical Trial
分子量

148.16

性状

Solid

Formula

C6H12O4

CAS 号

150-97-0

结构分类
  • Ketones, Aldehydes, Acids
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month