Euparin, a monomeric compound of Benzofuran, is areactive oxygen species(ROS)inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects^[1][2].

In Vero cells, Euparin shows antiviral activity against poliovirus types 1, 2, and 3 with EC₅₀values of 0.47 μg/mL, 0.12 μg/mL, and 0.15 μg/mL, respectively^[1].

Euparin (8, 16 and 32 mg/kg) reduces depression-like behavior in Chronic Unpredictable Mild Stress (CUMS) model of mice. All doses of Euparin are found to increase the contents of monoamine neurotransmitter and decrease monoamine oxidase and reactive oxygen species (ROS) levels in brain of depression mice. Euparin restores CUMS-induced decrease of Spermidine/Spermine N1-Acetyltransferase 1 (SAT1), N-methyl-D-aspartate receptor subtype 2B (NMDAR2B) and brain derived neurotrophic factor (BDNF) expression^[2].

216.23

Solid

C₁₃H₁₂O₃

532-48-9

泽兰素

• Phenols
• Monophenols

• Plants
• Leguminosae
• Guilandina minax(Hance) G. P. Lewis

• Plants
• Compositae

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)