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1-O-Hexadecyl-sn-glycerol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1-O-Hexadecyl-sn-glycerol图片
CAS NO:506-03-6
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议
1g电议

产品介绍
Cas No.506-03-6
别名鲛肝醇,α-Chimyl Alcohol, (S)-(+)-Chimyl Alcohol
化学名3-(hexadecyloxy)-1,2S-propanediol
Canonical SMILESCCCCCCCCCCCCCCCCOC[C@@H](O)CO
分子式C19H40O3
分子量316.5
溶解度0.16 mg/ml in DMSO, 16 mg/ml in DMF, 5 mg/ml Ethanol
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-O-Hexadecyl-sn-glycerol is a bioactive alkyl glyceryl ether. It reduces UVB-induced cell death and production of reactive oxygen species (ROS) and prostaglandin E2 in normal human epidermal keratinocytes (NHEKs). 1-O-Hexadecyl-sn-glycerol (50 μM) increases coronary flow and left ventricular developed pressure and reduces malondialdehyde (MDA) formation ex vivo in a rat heart model of ischemia/reperfusion injury.

References:
[1].Yokota, M., Yahagi, S., Tokudome, Y., et al. Chimyl alcohol suppresses PGE2 synthesis by human epidermal keratinocytes through the activation of PPAR-γ J. Oleo. Sci. 67(4), 455-462 (2018).

[2].Maulik, N., Tosaki, A., Engelman, R.M., et al. Myocardial salvage by chimyl alcohol: Possible role of peroxisomal dysfunction in reperfusion injury Ann. N.Y. Acad. Sci. 723(1), 380-384 (1994).