Lecanoric acid 是一种从真菌中分离出来的组氨酸脱羧酶抑制剂。
| Cas No. | 480-56-8 |
| 别名 | 紅粉苔酸 |
| 化学名 | 2,4-dihydroxy-6-methyl-benzoic acid, 4-carboxy-3-hydroxy-5-methylphenyl ester |
| Canonical SMILES | CC1=CC(OC(C2=C(C)C=C(O)C=C2O)=O)=CC(O)=C1C(O)=O |
| 分子式 | C16H14O7 |
| 分子量 | 318.3 |
| 溶解度 | DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens. It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively). Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 μg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties. |
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