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Worenine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Worenine图片
CAS NO:38763-29-0
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Worenine 分离自黄连。Worenine 在大鼠体内第一阶段代谢中显示出脱氢,氢化,羟基化和脱亚甲基反应。在大鼠体内 II 期代谢中主要为为硫酸化和葡萄糖醛酸化反应。
Cas No.38763-29-0
别名甲基黄连碱
Canonical SMILESCC1=C2C(C=C3OCOC3=C2)=C[N+]4=C1C(C(CC4)=C5)=CC6=C5OCO6
分子式C20H16NO4
分子量334.34
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Worenine is isolated from Coptis chinensis. Worenine in rat shows dehydrogenization, hydrogenation, hydroxylation, and demethylene reactions in phase I metabolism. The phase II metabolism sulfation and glucuronidation reactions[1].

[1]. Chen H, et al. Characterization of metabolites of worenine in rat biological samples using liquid chromatography-tandem mass spectrometry.J Pharm Biomed Anal. 2010 Jan 5;51(1):236-43.