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PF-CBP1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PF-CBP1图片
CAS NO:1962928-21-7
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
PF-CBP1是CREB结合蛋白溴区的高度选择性抑制剂。
生物活性

PF-CBP1 is a highly selective inhibitor of the CREB binding protein bromodomain[1].

体外研究
(In Vitro)

PF-CBP1 modulates key inflammatory genes in primary macrophages. PF-CBP1 downregulates RGS4 in neurons, a target linked to Parkinson's disease. PF-CBP1 is 139-fold selective over BRD4 in the biochemical assays and >105-fold selective by ITC. F-CBP1 is also a potent inhibitor of EP300 (a result observed for other CBP inhibitors[1].

分子量

488.62

Formula

C29H36N4O3

CAS 号

1962928-21-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.