CAS NO: | 1782532-06-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | PD 168568 dihydrochloride is a orally active and potentdopamine receptorD4(DRD4)antagonist. PD 168568 dihydrochloride contains an isoindolinone and is selective for theD4receptorversus D2and D3, withKivalues of 8.8, 1842, and 2682 nM, respectively. PD 168568 dihydrochloride can be used for glioblastoma (GBM) research[1][2]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | PD 168568 dihydrochloride 对胶质母细胞瘤神经干细胞 (GNS) 表现出选择性抑制,IC50为 25-50 μM[1]。 | ||||||||
体内研究 (In Vivo) | PD 168568 dihydrochloride (3 mg/kg,口服) 可抑制大鼠 amphetamine 刺激的运动活动[3]。
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分子量 | 422.39 | ||||||||
Formula | C22H29Cl2N3O | ||||||||
CAS 号 | 1782532-06-2 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |